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Table 1 General characteristics of 160 HLH patients according to survival groups

From: Clinical profiles and risk factors of 7-day and 30-day mortality among 160 pediatric patients with hemophagocytic lymphohistiocytosis

Factor All (N = 160) Survival days a
> 30 days (n = 108) ≤30 days (n = 46) ≤7 days (n = 18)
n(%) n(%) n(%) p value b n(%) p value c
Age
  ≤ 12 months 25 (15.6) 15 (13.9) 10 (21.7) 0.3795 6 (33.3) 0.0307
  > 1 and ≤ 5 years 102 (63.8) 69 (63.9) 28 (60.9)   9 (50.0)  
  > 5 and ≤ 10 yeas 22 (13.8) 16 (14.8) 5 (10.9)   1 (5.6)  
  > 10 years 10 (6.3) 8 (7.4) 2 (4.3)   1 (5.6)  
Sex
 Male 90 (56.3) 62 (57.4) 24 (52.2) 0.597 11 (61.1) 0.659
 Female 70 (43.8) 46 (42.6) 22 (47.8)   7 (38.9)  
Hospital admission
 PICU 66 (41.3) 35 (32.4) 28 (60.9) 0.0013 11 (61.1) 0.0692
 Other department 94 (58.8) 73 (67.6) 18 (39.1)   7 (38.9)  
Discharge department
 PICU 73 (45.6) 25 (23.1) 45 (97.8) < 0.0001 18 (100) < 0.0001
 Other department 87 (54.4) 83 (76.9) 1 (2.2)   0  
First symptom to indicated hospital admission (days) d 8.0 (6.0, 12.0) 8.0 (6.0, 12.0) 8.0 (6.0, 11.0) 0.8188 8.5 (6.0, 12.0) 0.8281
  1. a. Six patients were lost follow-up at day 30
  2. b. Compared with patients survived > 30 days
  3. c. Compared with patients survived > 7 days
  4. d. Median (Q1, Q3)