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Table 1 General characteristics of 160 HLH patients according to survival groups

From: Clinical profiles and risk factors of 7-day and 30-day mortality among 160 pediatric patients with hemophagocytic lymphohistiocytosis

Factor

All (N = 160)

Survival days a

> 30 days (n = 108)

≤30 days (n = 46)

≤7 days (n = 18)

n(%)

n(%)

n(%)

p value b

n(%)

p value c

Age

  ≤ 12 months

25 (15.6)

15 (13.9)

10 (21.7)

0.3795

6 (33.3)

0.0307

  > 1 and ≤ 5 years

102 (63.8)

69 (63.9)

28 (60.9)

 

9 (50.0)

 

  > 5 and ≤ 10 yeas

22 (13.8)

16 (14.8)

5 (10.9)

 

1 (5.6)

 

  > 10 years

10 (6.3)

8 (7.4)

2 (4.3)

 

1 (5.6)

 

Sex

 Male

90 (56.3)

62 (57.4)

24 (52.2)

0.597

11 (61.1)

0.659

 Female

70 (43.8)

46 (42.6)

22 (47.8)

 

7 (38.9)

 

Hospital admission

 PICU

66 (41.3)

35 (32.4)

28 (60.9)

0.0013

11 (61.1)

0.0692

 Other department

94 (58.8)

73 (67.6)

18 (39.1)

 

7 (38.9)

 

Discharge department

 PICU

73 (45.6)

25 (23.1)

45 (97.8)

< 0.0001

18 (100)

< 0.0001

 Other department

87 (54.4)

83 (76.9)

1 (2.2)

 

0

 

First symptom to indicated hospital admission (days) d

8.0 (6.0, 12.0)

8.0 (6.0, 12.0)

8.0 (6.0, 11.0)

0.8188

8.5 (6.0, 12.0)

0.8281

  1. a. Six patients were lost follow-up at day 30
  2. b. Compared with patients survived > 30 days
  3. c. Compared with patients survived > 7 days
  4. d. Median (Q1, Q3)