Table 2 Organ involvement of patients with immune-mediated thrombotic thrombocytopenic purpura.
|  | primary iTTP (n = 18)a | SLE-TTP (n = 10)a | p values |
|---|---|---|---|
CNS involvement, n | 18 (100.0) | 10 (100.0) | 1.00 |
Severe | 17 (94.4) | 10 (100.0) | 1.00 |
Seizure | 13 (72.2) | 4 (40.0) | 0.12 |
Coma | 15 (83.3) | 7 (70.0) | 0.63 |
Stroke | 3 (16.7) | 3 (30.0) | 0.63 |
Psychosis | 0 (0.0) | 2 (20.0) | 0.12 |
Renal involvement | |||
 Serum creatinine, μmol/L | 162.7 ± 110.6 | 73.3 ± 13.4 | < 0.01 |
 BUN, μmol/L | 15.4 ± 10.1 | 7.9 ± 2.7 | < 0.01 |
 AKI | 13 (72.2) | 1 (10.0) | < 0.01 |
 Stage 1 | 5 (27.8) | 1 (10.0) | 0.37 |
 Stage 2 | 6 (33.3) | 0 (0.0) | 0.06 |
 Stage 3 | 2 (11.1) | 0 (0.0) | 0.52 |
Proteinuria level, dipstick | |||
 Negative | 2 (11.1) | 1 (10.0) | 1.00 |
 Mild (± to +) | 7 (38.9) | 6 (60.0) | 0.43 |
 Moderate (++) | 9 (50.0) | 2 (20.0) | 0.22 |
 Large (+++) | 0 (0.0) | 1 (10.0) | 0.36 |
Cardiac involvement | |||
 cTnI (μg/L) | 0.47 (0.11, 1.00) | 0.10 (0.05, 0.64) | 0.36 |
 cTnI> 0.25 μg/L | 13 (72.2) | 5 (50.0) | 0.41 |
 MAP, mmHg | 85.3 ± 11.9 | 94.6 ± 13.9 | 0.08 |