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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Distinct promoter methylation patterns of LKB1 in the hamartomatous polyps of Peutz-Jeghers syndrome and its potential in gastrointestinal malignancy prediction

Fig. 3

Distinct promoter methylation patterns of LKB1 in hamartomatous polyps of PJS patients. a-c Representative of three methylation patterns of LKB1 promoter region presented by lollipop graph. a: hyper-methylated pattern; b: hemi-methylated pattern; c: hypo-methylated pattern. d Linear plot for the average methylation level of LKB1 promoter region for all the above patterns. e Diagram of three possible scenarios for different methylation patterns. M = maternal allele, P = paternal allele

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