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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Distinct promoter methylation patterns of LKB1 in the hamartomatous polyps of Peutz-Jeghers syndrome and its potential in gastrointestinal malignancy prediction

Fig. 2

Characterization of DNMTs’ expression in normal colon mucosa, PJS polyps, and colorectal cancer of PJS patients. a-c DNMT1 expression in the above samples. The expression of DNMT1 is increased in PJS polyps and colorectal cancer in PJS patients compared with normal mucosa. n = 15 (d-f) DNMT3a expression in the above samples. The expression of DNMT3a is increased in PJS polyps and colorectal cancer in PJS patients compared with normal mucosa. n = 15 (g-i) DNMT3b immunochemistry results shows negative staining in all the above samples. n = 15. Bar = 100 μm

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172