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Table 1 Median age at first symptoms, diagnosis and median time to diagnosis

From: Pediatric hypophosphatasia: lessons learned from a retrospective single-center chart review of 50 children

Age (in months)

Perinatal HPP

Infantile HPP

Childhood HPP

All Subtypes

Median age at first symptoms

(min. 0; max. 0)

2 (0; 14)

9 (0; 107)

3.5 (0; 107)

Median age at diagnosis

0 (0; 0)

15 (2; 49)

36 (3; 127)

24 (0; 127)

Median time to diagnosis

0 (0; 0)

12 (1; 45)

22.5 (0; 103)

13 (0; 103)

♂: 12 (2; 24)

♂: 21 (0; 86)

♂: 13 (0; 103)

♀: 9 (1; 45)

♀: 22.5 (0; 103)

♀: 15.5 (0; 86)