Skip to main content

Table 4 WPAI Sub-scores Stratified by Caregiver and Affected Individual

From: Quality of life data for individuals affected by spinal muscular atrophy: a baseline dataset from the Cure SMA Community Update Survey

Functional Status Caregiver Affected Adult Overall Significance testinga
Mean (SD) Sample Size Mean (SD) Sample Size Mean (SD) Sample Size P value
Permanent Ventilation
 Absenteeism, % 7.6 (9.1) 4 N/A N/A 6.1 (8.6) 5 N/A
 Presenteeism, % 76.4 (31.1) 11 N/A N/A 73.1 (34.7) 13 N/A
 Overall Impairment, % 59.0 (43.3) 4 N/A N/A 49.2 (43.4) 5 N/A
 Activity Impairment, % 83.1 (20.9) 35 68.8 (25.3) 8 80.5 (22.2) 43 0.13b
Non-sitters
 Absenteeism, % 13.3 (15.1) 16 6.4 (13.6) 15 10.0 (14.6) 31 0.09b
 Presenteeism, % 47.0 (31.8) 23 36.7 (29.5) 18 42.4 (30.9) 41 0.29
 Overall Impairment, % 50.1 (27.3) 16 37.2 (28.8) 15 43.9 (28.3) 31 0.21
 Activity Impairment, % 60.8 (29.4) 50 69.1 (21.5) 34 64.2 (26.7) 84 0.14
Sitters
 Absenteeism, % 18.8 (29.0) 36 6.8 (12.1) 31 13.3 (23.4) 67 0.04*
 Presenteeism,  % 41.6 (31.0) 45 44.5 (30.1) 40 42.9 (30.5) 85 0.66
 Overall Impairment, % 44.6 (29.6) 33 41.0 (23.7) 30 42.9 (26.8) 63 0.59
 Activity Impairment, % 60.9 (25.2) 123 55.2 (22.6) 65 58.9 (24.4) 188 0.09b
Walk with Support
 Absenteeism, % 16.3 (11.5) 6 8.5 (11.8) 4 13.2 (11.6) 10 0.34
 Presenteeism, % 55.0 (31.2) 8 50.0 (33.7) 4 53.3 (30.6) 12 0.93b
 Overall Impairment, % 62.7 (19.5) 6 53.2 (35.5) 4 58.9 (25.6) 10 0.59b
 Activity Impairment, % 50.0 (26.5) 27 7.0 (61.4) 7 52.4 (26.3) 34 0.22b
Walk Independently
 Absenteeism, % 4.4 (8.1) 6 6.8 (15.1) 12 6.0 (12.9) 18 0.91b
 Presenteeism, % 17.5 (22.5) 8 37.3 (25.5) 15 30.4 (25.8%) 23 0.07
 Overall Impairment, % 25.5 (26.5) 6 35.5 (28.1) 12 32.2 (27.2) 18 0.40b
 Activity Impairment, % 41.2 (24.2) 25 55.0 (22.3) 26 48.2 (24.1) 51 0.02*,b
  1. a Significance testing between work productivity of a caregiver and an affected adult
  2. *Statistically significant at p < 0.05
  3. b Mann-Whitney test used to test for significance