Table 1 Post-treatment clinical characteristics of patients according to outcome
From: A novel prognostic model for adult patients with Hemophagocytic Lymphohistiocytosis
Characteristics | Survivors, n = 65 | Nonsurvivors, n = 71 | P-value |
|---|---|---|---|
Gender (male/female), n | 31/34 | 47/24 | 0.066 |
Median age (range), y | 48 (18–78) | 52 (18–78) | 0.104 |
Ferritin (μg/L) | 933.1 (45.3, > 15,000) | 3740 (250, > 15,000) | < 0.001 |
FIB (g/L) | 2.29 ± 1.05 | 1.95 ± 1.04 | 0.113 |
Neutrophils (×109/L) | 3.80 ± 3.06 | 3.12 ± 3.76 | 0.253 |
HB (g/L) | 99.88 ± 18.58 | 88.41 ± 19.26 | 0.001 |
Platelet (×109/L) | 118.51 ± 75.10 | 55.79 ± 66.02 | < 0.001 |
ALT (U/L) | 90.8 ± 131.36 | 200.61 ± 449.48 | 0.060 |
AST (U/L) | 84.39 ± 154.33 | 302.64 ± 562.74 | 0.003 |
LDH (U/L) | 420.99 ± 330.20 | 1561.83 ± 2604.34 | 0.001 |
α-HBDH (U/L) | 270.17 ± 178.31 | 780.96 ± 1095.77 | < 0.001 |
DB (μmol/L) | 7.83 ± 9.41 | 35.09 ± 51.60 | < 0.001 |
TG (mmol/L) | 2.02 ± 1.16 | 4.14 ± 8.59 | 0.051 |
HDL (mmol/L) | 1.08 ± 0.45 | 0.94 ± 2.09 | 0.589 |
LDL (mmol/L) | 2.73 ± 1.20 | 2.64 ± 3.26 | 0.883 |
Albumin (g/L) | 33.16 ± 5.35 | 27.50 ± 5.01 | < 0.001 |
Glucose (mmol/L) | 5.67 ± 2.58 | 6.19 ± 2.77 | 0.262 |
UREA (mmol/L) | 5.84 ± 2.57 | 10.81 ± 9.05 | < 0.001 |
CREA (μmol/L) | 53.42 ± 38.57 | 94.80 ± 115.76 | 0.007 |
UA (μmol/L) | 218.61 ± 97.35 | 311.69 ± 229.97 | 0.003 |
Ca2+ (mmol/L) | 2.15 ± 0.16 | 2.02 ± 0.19 | < 0.001 |