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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Inhibition of the mechanistic target of rapamycin induces cell survival via MAPK in tuberous sclerosis complex

Fig. 4

Rapamycin promotes MAPK signaling pathway in TSC2 deficient cells. Immunoblots of TSC2-deficient (a) patient-derived cells, b rat uterine leiomyoma-derived cell, c Tsc2−/− MEFs, and d Tsc1−/− MEFs, treated with rapamycin at indicated time points. Immunoblotting analyses of TSC2, phospho-MAPK (T202/Y204), and phospho-S6 (S235/236) were shown

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172