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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Inhibition of the mechanistic target of rapamycin induces cell survival via MAPK in tuberous sclerosis complex

Fig. 3

Rapamycin is cytostatic but not cytotoxic in vitro. a Cell proliferation of TSC2-deficient patient-derived cells treated with escalating concentrations of rapamycin. b Phase contrast microscopy of TSC2-deficient patient-derived, rat uterine leiomyoma-derived, Tsc2−/− MEFs and Tsc1−/− MEFs treated with rapamycin. c Propidium iodide exclusion assay of TSC2-deficient patient-derived cells treated with escalating concentrations of rapamycin as indicated. ** P < 0.01, the Student’s t-test

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172