Table 2 Clinical characteristics of the NF1 Cohort
| Â | NF1 patients (n = 42) | |
|---|---|---|
Mean age (years) ± SD | 11.33 ± 4.25 |  |
Range | 4–20 |  |
| Â | n | (%) |
Gender | ||
 Male | 19 | (45.2%) |
 Female | 23 | (54.8%) |
Clinical criteria met for NF1 | 42 | (100%) |
OPG (Optic Pathway Glioma) | 14 | (33.3%) |
 Stable OPG on brain MRI | 11 | (78.6%) |
 Regressed OPG on brain MRI | 2 | (14.3%) |
 Worsened OPG on brain MRI | 1 | (7.1%) |
Other CNS tumors | 5 | (11.9%) |
 Neurosurgical treatment | 2 | (40.0%) |
 Chemotherapy | 1 | (20.0%) |
Plexiform neurofibromas (NF) | 12 | (28.6%) |
Plexiform NF treated with surgery | 2 | (16.6%) |
Received IQ assessment | 42 | (100%) |
Median IQ ± SD Range | 94.32 ± 14.89 59–113 |  |
 Normal IQ | 33 | (78.6%) |
 BIF | 5 | (11.9%) |
 Mild ID | 4 | (9.5%) |
 Moderate/severe ID | 0 | (0.0%) |
Received formal psychiatric assessmen | 15 | (35.7%) |
 ASD | 0 | (0.0%) |
 ADHD | 7 | (46.6%) |
 Anxious/Depressed Disorder | 5 | (33.3%) |
Additional support in school (i.e. IEP) | 21 | (50.0%) |
SLD | 9 | (21.4%) |
Low self-esteem (per parents’ report) | 15 | (35.7%) |
Very high levels of stress in families | 14 | (33.3%) |
Very high levels of stress between parents | 8 | (19.0%) |