Pregnancy in GNE myopathy patients: a nationwide repository survey in Japan

Table 4 Complications during delivery in post-onset deliveries among GNE myopathy patients

		General population (Japanese)	Post-onset deliveries (n = 23)	Comparison
		Frequency %	Frequency % [95% CI]	P value
Type of delivery	Vaginal delivery	81.9 [18]	82.6 [61.2-95.0]	1
	Cesarean section (CS)	18.1 [18]	17.4 [5.0-38.8]	1
	Emergency CS	13.7^a	4.3 [0.1-21.9]	0.15
	Previous CS	8.1 [18]	8.7 [1.1-28.0]	0.71
	Breech presentation	2.4 [21]	4.3 [0.1-21.9]	0.43
Beginning of vaginal delivery^b	Spontaneous labor		66.7 [41.0-87.7]
	PROM	10-20 [22]^c	16.7 [3.6-41.4]
	Bleeding		0.0 [0.0-18.5]
	Induced labor		16.7 [3.6-41.4]
	Fetal abnormality		0.0 [0.0-18.5]
	Maternal abnormality		0.0 [0.0-18.5]
	Overdue pregnancy		5.6 [0.1-27.3]
	Scheduled		11.1 [1.4-34.7]
Outcomes of vaginal delivery^d,e	No assistance		78.9 [54.4-93.9]
	Vacuum extraction	7.6 [18]	10.5 [1.3-33.1]	0.39
	Manual fundal pressure	11.2 [23]	15.8 [3.4-39.6]	0.46
	Forceps delivery	0.3 [18]	0.0 [0.0-17.6]
Management	Labor augmentation^f		33.3 [13.3-59.0]
Management	Blood transfusion	0.5 [17]	0.0 [0.0-14.8]	1
Number of fetuses	Singletons	98.1 [17]	100.0 [85.1-100.0]	1
Complications after delivery	Maternity blues		4.3 [0.1-21.9]
	Postnatal depression		0.0 [0.0-14.8]
	Deep vein thrombosis		0.0 [0.0-14.8]
	Intrauterine infection		0.0 [0.0-14.8]
	Mastitis		0.0 [0.0-14.8]
	Prolapsed uterus		0.0 [0.0-14.8]

PROM Premature rupture of the membrane
^aAnalyzed 3109 deliveries at Tokyo Medical and Dental University from 2013-2019
^bAnalyzed 18/19 post-onset vaginal deliveries due to missing data (no response)
^cFrequency among deliveries
^dAnalyzed 19/19 post-onset vaginal deliveries
^eMultiple choices allowed
^fAnalyzed 18/23 post-onset deliveries due to missing data (no response)
* p <0.05

ISSN: 1750-1172