Skip to main content

Table 1 Participant background characteristics

From: Pregnancy in GNE myopathy patients: a nationwide repository survey in Japan

Age    Average [SD] Median [Min-Max]
Age at survey (yrs) Participants (n = 44) 51.0 [11.1] 49.5 [32-76]
Onset age (yrs)a 33.0 [9.8] 30 [16-62]
Maternal age (yrs) Post-onset pregnancies (n = 28) 32.5 [4.4] 31.5 [23-40]
Pre- and post-onset pregnancies (n = 81) 29.1 [5.0] 29.0 [19-40]
Genetic diagnosis    Frequency
% [95% CI]
Homozygotesa Participants (n = 44) 8.9 [2.5-21.2]
Compound heterozygotesa 91.1 [78.8-97.5]
c.620A>T (p.D207V) a Alleles (n = 88) 35.2 [25.3-46.1]
c.1807G>C (p.V603L) a 30.7 [21.3-41.4]
Parity    n   n
0 Post-onset pregnancies (n = 28) 13 Pre- and post-onset pregnancies (n=81) 48
1 11 29
2 or more 4 4
Walking ability at pregnancy    Frequency
% [95%CI ]
No assistance Post-onset pregnancies (n = 27b) 85.1 [66.2-95.8]
Using assistive devices 14.8 [4.2-33.7]
Unable to walk 0.0 [0.0-12.8]
  1. aData from the Remudy database. Other data are from the questionnaire
  2. bAnalyzed 27/28 post-onset pregnancies due to missing data (no response)