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Table 1 Gastrointestinal symptoms and procedures in our cohort

From: Alternating Hemiplegia of Childhood: gastrointestinal manifestations and correlation with neurological impairments

Symptoms
Upper Gastrointestinal Symptoms Number of Patients Per Symptom
Dysphagia 26
Vomiting 26
Weight Loss/Failure to Thrive/Anorexia 19
Nausea 15
Sialorrhea 8
Lower Gastrointestinal Symptoms Number of Patients Per Symptom
Constipation 27a
Diarrhea 18a
Abdominal Pain 9b
Procedures
Type of Procedure Number of Patients with Abnormal Results/Total Number of Patients Undergoing the Test (% of patients)
Video Fluoroscopic Swallow Study 10/10 (100%)
Upper Endoscopy 2/7 (28.5%)
Nuclear Medicine Gastric Emptying Study 4/5 (80%)
Upper GI X-Ray Series 0/4 (0%)
Abdominal Ultrasound 0/2 (0%)
Colonoscopy w/ Biopsy 0/2 (0%)
Upright Modified Barium Swallow Study 1/1 (100%)
CT Abdomen 1/1 (100%)c
Anorectal Manometry 0/1 (0%)
  1. a33/41 patients with gastrointestinal symptoms exhibited either constipation or diarrhea. Of these 33 patients, 12 had both constipation and diarrhea manifesting as alternating episodes, 6 had only diarrhea, and 15 had only constipation
  2. b In most patients, it was not possible to definitely localize the pain to the upper or lower abdomen, due to their limited ability to communicate
  3. cCT scan showed changes indicative of constipation