| |
Baseline
|
Month 6
|
Wilcoxon p-value
|
|---|
|
6MWT (meters)
|
316.88 ± 123.26
|
345.50 ± 117.68
|
0.11
|
|
BARS score
|
9.75 ± 6.09
|
10.06 ± 6.96
|
0.59
|
|
Neuroglyphics Off Target-dominant (%)
|
19.00 ± 14.11
|
16.62 ± 10.91
|
0.69
|
|
Neuroglyphics Off Target- Nd (%)
|
21.19 ± 13.99
|
17.77 ± 11.65
|
0.47
|
|
BARS Upper score
|
2.63 ± 2.22
|
2.75 ± 2.84
|
0.79
|
|
9HP Dom Avg (sec)
|
28.83 ± 8.23
|
27.22 ± 7.84
|
0.38
|
|
9HP Dom z-score (sec)
|
4.35 ± 2.77
|
4.04 ± 2.77
|
0.38
|
|
9HP Nd Avg (sec)
|
30.89 ± 15.88
|
29.84 ± 11.41
|
0.78
|
|
9HP Nd z-score (sec)
|
4.71 ± 5.39
|
5.05 ± 4.96
|
1
|
|
GAITRite data:
|
|
Cadence (steps/min)
|
94.33 ± 18.86
|
99.95 ± 13.88
|
0.15
|
|
Velocity (cm/sec)
|
97.86 ± 34.08
|
108.59 ± 33.61
|
0.15
|
|
Step Length (cm)
|
60.10 ± 12.74
|
63.68 ± 14.62
|
0.38
|
|
Step Width (cm)
|
11.72 ± 3.77
|
11.53 ± 3.46
|
0.55
|
|
Step Time (sec)
|
0.67 ± 0.15
|
0.61 ± 0.09
|
0.11
|
- Avg Average, BARS Brief Ataxia Rating Scale, cm Centimetres, DOM Dominate min Minute, 6MWT 6-min walk test, Nd Non-dominant, sec Seconds, 9HP 9-hole peg test – a brief, standardized and quantitative test of upper extremity (hand and arm) function z-score: calculated by converting raw into a common metric
