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Table 1 Baseline Characteristics of HHT Patient Cohort

From: Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding

Clinical Variables

Reference Range

Mean ± Standard Deviation or n (%)

Race

 Caucasian

 

134 (89.9)

 Non-Caucasian

 

15 (10.1)

Sex

 Male

 

91 (61.1)

 Female

 

58 (38.9)

Age, y

 

50.6 ± 16.1 (range 18–89)

Epistaxis Severity Score

 

4.03 ± 2.34

Hemoglobin (Hgb, g dL−1)

13.5–17.5

12.12 ± 2.62a

Hematocrit (Hct, %)

36–46

37.4 ± 6.76b

Mean Cell Volume (MCV, fL)

80–100

85.38 ± 8.24c

Mean Corpuscular Hemoglobin Concentration (MCHC g dL− 1)

31–37

32.4 ± 1.97b

Iron (μg dL− 1)

35–165

63.10 ± 47.8d

Transferrin (Tfn, mg dL− 1)

200–380

307.42 ± 54.43e

Total iron-binding capacity (TIBC μg dL− 1)

252–479

383.08 ± 69.27f

Iron saturation (%)

20–50

17.73 ± 15.16e

Ferritin (ng mL− 1)

27–377

29.31 ± 49.96g

  1. Number of patients is n = 149, unless denoted by footnote as below
  2. an = 65
  3. bn = 73
  4. cn = 66
  5. dn = 85
  6. en = 88
  7. fn = 87
  8. gn = 76