Characterization of CT scans of patients with Birt-Hogg-Dubé syndrome compared with those of Chinese patients with non-BHD diffuse cyst lung diseases

Table 2 Radiological characteristics of pulmonary cysts in BHD and non-BHD

Characteristic	BHD N = 33	LAM N = 33	NBNL DCLD N = 23	P*	P**	P***
Cranial-caudal distribution
Upper lung, N (%)	2 (6)	0 (0)	6 (26)	< 0.001	0.473	0.086
Lower lung, N (%)	19 (58)	0 (0)	6 (26)	< 0.001	< 0.001	0.020
Diffuse, N (%)	12 (36)	33 (100)	11 (48)	< 0.001	< 0.001	0.391
Axial distribution
Mediastinum, N (%)	18 (55)	0 (0)	0 (0)	< 0.001	< 0.001	< 0.001
Peripheral pleural, N (%)	3 (9)	0 (0)	0 (0)	0.074	0.237	0.237
Diffuse, N (%)	12 (36)	33 (100)	23 (100)	< 0.001	< 0.001	< 0.001
Fusiform Cysts, N (%)	27 (82)	5 (15)	5 (22)	< 0.001	< 0.001	< 0.001
No. of Lung Cysts
<10, N (%)	2 (6)	0 (0)	0 (0)	0.180	0.473	0.638
10–20, N (%)	4 (12)	0 (0)	0 (0)	0.030	0.122	0.228
20–50, N (%)	13 (39)	0 (0)	5 (22)	< 0.001	< 0.001	0.164
>50, N (%)	14 (42)	33 (100)	18 (78)	< 0.001	< 0.001	0.008
Maximum Cyst
Lower lung, N (%)	28 (85)	11 (33)	10 (43)	0.023	< 0.001	0.001
Bigger cyst diameter, median (IQR)	45 (30, 55)	16.5 (10,20)	35 (20,50)	< 0.001	< 0.001	0.121

P*values are for comparison within the three groups together by Kruskal-Wallis test
P**values are for comparison between the BHD and LAM groups
P*** values are for comparison between the BHD and NBNL DCLD groups
The P value was calculated with the use of Pearson’s chi-squared test for categorical variables
The P value was calculated with the use of the Wilcoxon rank-sum test to compare continuous variables

ISSN: 1750-1172