Characterization of CT scans of patients with Birt-Hogg-Dubé syndrome compared with those of Chinese patients with non-BHD diffuse cyst lung diseases

Table 1 Demographic features of the BHD and non-BHD groups

Characteristic	BHD N = 33	LAM N = 33	NBNL DCLD^a N = 23	P*	P**
Female, N (%)	31 (93.9)	33 (100)	18 (78.3)	0.473	0.182
Age of diagnosis, Mean (SD)	48 ± 12	37 ± 8	40 ± 14	< 0.001	0.020
Pneumothorax antecedent, N (%)	17 (51.5)	12 (36.4)	3 (13.0)	0.215	0.003
Smoking history, N (%)	1 (3.0)	0 (0)	8 (34.8)	0.314	0.001
Family history, N (%)	25 (75.8)	0 (0)	0 (0)	< 0.001	< 0.001

*P values are for comparison between the BHD and LAM groups
**P values are for comparison between the BHD and NBNL DCLD groups
^aThe NBNL (no-BHD and no-LAM) DCLD group includes 15 cases of lymphocytic interstitial pneumonia associated with Sjogren’s syndrome (SS), 7 cases of pulmonary Langerhans cell histiocytosis (PLCH), 1 case with Langerhans cell histiocytosis (LCH) and 1 case of Castleman Disease
The P value was calculated with the use of the unpaired t-test to compare continuous variables
The P value was calculated with the use of Pearson’s chi-squared test for categorical variables
Abbreviations: BHD Birt-Hogg-Dubé syndrome, DCLD diffuse cystic lung disease, NBNL no-BHD and no-LAM, SD standard deviation

ISSN: 1750-1172