Fig. 2

Muscle imaging of LGMD1E, 2A, 2B, 2G, and 2Q. Muscle CT images of 1E revealed most involvement in the S and ST, and less involvement in the VL and VIM at thigh level and the SO, TA, and TP muscles at calf level (a, b, c). Compared with LGMD2A (d, e, f), gluteal muscles were less affected but the TA was more severely involved in LGMD2B (g, h, i). LGMD2G exhibited severe involvement of the gluteus, long head of the BF, AM, ST, SM, SO, medial head of GC, and TA muscles; the short head of BF, AL, S, FD, HL, and lateral head of GC muscles were relatively spared (j, k, l). For LGMD2Q (m, n, o), in the thigh, the AM as well as S and G were relatively hypertrophic and preserved; by contrast, the ST, SM, and QF (except for RF) were markedly affected. At calf level, the GC and P were involved, whereas the TA and EL muscles were preserved and slightly hypertrophic. (AM: adductor magnus; AL: adductor longus; BF: biceps femoris; EL: extensor longus; FD: flexor digitorum; G: gracilis; GC: gastrocnemius; HL: hallucis longus; P: peroneus; QF: quadriceps femoris; RF: rectus femoris; S: sartorius; SO: soleus; ST: semitendinosus; SM: semimembranosus; TA: tibialis anterior; TP: tibialis posterior; VL: vastus lateralis; VIM: vastus intermedius)