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Table 2 Symptoms and sign of Covid-19 infection and management in cardiomyopathies (CMP) and ion channel diseases (ICD). HFpEF: heart failure with preserved ejection fraction; HFrEF: heart failure with reduced ejection fraction

From: COVID-19 pandemia and inherited cardiomyopathies and channelopathies: a short term and long term perspective

SYMPTOMCLINICAL CONTEXTMANAGEMENT
Feveranamnesis: previous contact with Covid19+, onset, and progression, degree (>or < 37.5°), association with other symptomsHydratation (according to clinical status) and paracetamol
ECG monitoring in Brugada Syndrome. Consider hospitalization in high risk patients (BS type 1 with no ICD; previous syncope; persistent fever, with no response to paracetamol)
Coughanamnesis: previous contact with Covid19+, type of cough (productive or dry), previous or recent onset, association with other symptomsTeleconsultation
ProBNP or BNP (suspect of new onset heart failure), when possible
Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Dyspnoeaanamnesis: previous contact with Covid19+, type and degree, previous or recent onset, association with other symptomsTeleconsultation
ProBNP or BNP (suspect of new onset heart failure), when possible
Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Fatigueanamnesis: previous contact with Covid19+, type (i.e. myalgia, cramps, etc) and degree, previous of recent onset, association with other symptomsTeleconsultation
When useful, suggest potassium/magnesium supplementation
ProBNP or BNP (suspect of new onset heart failure), when possible
Consider hospitalization in high risk patients (emergency; end stage cardiomyopathies; high suspect of HFREF/HFPEF)
Diarrheaanamnesis: previous contact with Covid19+, association with other symptomsTeleconsultation
Hydratation (according to clinical status)
Risk of hypokaliemia particularly dangerous in patients with prolonged QT (LQTs, drugs, HCM)
Potassium/magnesium supplementation