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Table 3 Safety parameters in total group during the 3-yar study

From: Three years of growth hormone treatment in young adults with Prader-Willi syndrome: sustained positive effects on body composition

 At startAfter 1 yearAfter 2 yearsAfter 3 yearsP-value*
Fasting glucose (mmol/l)4.6 (4.4 to 4.8)4.7 (4.5 to 4.9)4.8 (4.6 to 4.9)4.6 (4.5 to 4.7)0.93
Fasting insulin (pmol/l)59.5 (45.2 to 81.5)67.6 (55.0 to 81.5)64.5 (51.6 to 78.7)55.0 (42.4 to 69.2)0.54
Systolic BP (mmHg)*120.2 (116.5 to 123.9)123.9 (120.6 to 127.1)122.7 (118.6 to 126.8)121.4 (116.4 to 126.3)0.68
Diastolic BP (mmHg)*73.1 (70.5 to 75.7)73.0 (71.1 to 75.0)74.3 (72.0 to 76.5)73.6 (70.9 to 76.3)0.78
  1. Data are expressed as estimated means (95% CI). BP Blood pressure. *corrected for sex and height
  2. *P-value of the change during 3 years of GH treatment