Table 3 Safety parameters in total group during the 3-yar study
At start | After 1 year | After 2 years | After 3 years | P-value* | |
|---|---|---|---|---|---|
Fasting glucose (mmol/l) | 4.6 (4.4 to 4.8) | 4.7 (4.5 to 4.9) | 4.8 (4.6 to 4.9) | 4.6 (4.5 to 4.7) | 0.93 |
Fasting insulin (pmol/l) | 59.5 (45.2 to 81.5) | 67.6 (55.0 to 81.5) | 64.5 (51.6 to 78.7) | 55.0 (42.4 to 69.2) | 0.54 |
Systolic BP (mmHg)* | 120.2 (116.5 to 123.9) | 123.9 (120.6 to 127.1) | 122.7 (118.6 to 126.8) | 121.4 (116.4 to 126.3) | 0.68 |
Diastolic BP (mmHg)* | 73.1 (70.5 to 75.7) | 73.0 (71.1 to 75.0) | 74.3 (72.0 to 76.5) | 73.6 (70.9 to 76.3) | 0.78 |