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Table 1 Baseline patient characteristics of the vehicle group

From: Wound closure in epidermolysis bullosa: data from the vehicle arm of the phase 3 ESSENCE Study

  Total
n = 87
Age Group Target Wound Age BSAi of Total Body Wound Burden EB Type
1 month to <2 years
n = 6
2 years to
<12 years
n = 47
12 years to <18 years
n = 12
≥18 years
n = 22
≤30 days
n = 25
>30 days
n = 62
<5%
n = 31
≥5%
n = 55
Simplex
n = 8
Recessive dystrophic
n = 62
Intermediate junctional
n = 17
Age, years
 Mean ± SD 13.9 ± 13.1 0.6 ± 0.3 6.8 ± 2.9 14.5 ± 1.8 32.5 ± 12.7 15.5 ± 15.8 13.3 ± 12.0 13.4 ± 15.2 14.0 ± 11.9 6.7 ± 9.1 11.5 ± 9.0 26.4 ± 19.1
 Min, Max 0.2, 67.0 0.2, 1.0 2.0, 11.0 12.0, 17.0 18.0, 67.0 0.5, 67.0 0.2, 59.0 0.2, 67.0 0.5, 59.0 0.2, 28.0 0.5, 48.0 2.0, 67.0
Sex, n (%)
 Male 39 (44.8) 3 (50.0) 25 (53.2) 4 (33.3) 7 (31.8) 13 (52.0) 26 (41.9) 15 (48.4) 24 (43.6) 5 (62.5) 28 (45.2) 6 (35.3)
 Female 48 (55.2) 3 (50.0) 22 (46.8) 8 (66.7) 15 (68.2) 12 (48.0) 36 (58.1) 16 (51.6) 31 (56.4) 3 (37.5) 34 (54.8) 11 (64.7)
EB Type, n (%)
 Simplex 8 (9.2) 3 (50.0) 4 (8.5) 0 1 (4.5) 1 (4.0) 7 (11.3) 5 (16.1) 3 (5.5) 8 (100) 0 0
 Recessive dystrophic 62 (71.3) 3 (50.0) 38 (80.9) 10 (83.3) 11 (50.0) 18 (72.0) 44 (71.0) 23 (74.2) 39 (70.9) 0 62 (100) 0
 Intermediate junctional 17 (19.5) 0 5 (10.6) 2 (16.7) 10 (45.5) 6 (24.0) 11 (17.7) 3 (9.7) 13 (23.6) 0 0 17 (100)
  1. BSAi Body surface area index, EB Epidermolysis bullosa, SD Standard deviation