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Table 5 Frequency of criterion for autism spectrum disorder for participants (n = 46) with complete ADI-R data (at age 5) by the two domains in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5)

From: Should autism spectrum disorder be considered part of CHARGE syndrome? A cross-sectional study of 46 patients

DSM-5Criterionn (%)
A. Communication and interactionDeficits in social-emotional reciprocity41 (89)
Deficits in nonverbal communicative behaviors used for social interaction36 (78)
Deficits in developing, maintaining, and understanding relationships Deficits in developing, maintaining, and understanding relationships38 (83)
B. Restrictive and repetitive patterns of behaviorsStereotyped or repetitive motor movements, use of objects, or speech34 (74)
Insistence on sameness, inflexible adherence to routines, or ritualized patterns or verbal nonverbal behavior26 (56)
Highly restricted, fixated interests that are abnormal in intensity or focus8 (17)
Hyper- or hyporeactivity to sensory input or unusual interests in sensory aspects of the environment14 (30)