Should autism spectrum disorder be considered part of CHARGE syndrome? A cross-sectional study of 46 patients

Table 5 Frequency of criterion for autism spectrum disorder for participants (n = 46) with complete ADI-R data (at age 5) by the two domains in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5)

DSM-5	Criterion	n (%)
A. Communication and interaction	Deficits in social-emotional reciprocity	41 (89)
	Deficits in nonverbal communicative behaviors used for social interaction	36 (78)
	Deficits in developing, maintaining, and understanding relationships Deficits in developing, maintaining, and understanding relationships	38 (83)
B. Restrictive and repetitive patterns of behaviors	Stereotyped or repetitive motor movements, use of objects, or speech	34 (74)
	Insistence on sameness, inflexible adherence to routines, or ritualized patterns or verbal nonverbal behavior	26 (56)
	Highly restricted, fixated interests that are abnormal in intensity or focus	8 (17)
	Hyper- or hyporeactivity to sensory input or unusual interests in sensory aspects of the environment	14 (30)