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Table 3 MFM scores at T0 and Y1 for patients older than 2 years

From: Effects of nusinersen after one year of treatment in 123 children with SMA type 1 or 2: a French real-life observational study

Age at treatment onset

 

T0

Y1

P

 

MFM total score

42 / 44 (4–87)

47 / 50 (6–78)

< 0.001

All patients (n = 68)

MFM D1

7 / 4 (0–83)

7 / 3 (0–50)

0.245

MFM D2

63 / 67 (1–100)

71 / 76 (2–100)

< 0.001

MFM D3

74 / 81 (10–100)

81 / 88 (14–100)

< 0.001

2–5 years

(n = 33)

MFM total score

45 / 45 (10–87)

52 / 53 (16–78)

< 0.001

MFM D1

10 / 4 (0–83)

10 / 4 (0–50)

0.144

MFM D2

66 / 71 (1–100)

77 / 83 (22–100)

< 0.001

MFM D3

74 / 83 (24–100)

84 / 92 (38–100)

0.001

6–17 years (n = 35)

MFM total score

40 / 43 (4–60)

43 / 47 (6–63)

0.099

MFM D1

4 / 3 (0–25)

3 / 3 (0–13)

0.651

MFM D2

61 / 63 (6–96)

64 / 69 (2–97)

0.457

MFM D3

73 / 81 (10–100)

79 / 86 (14–100)

0.04

  1. The values shown are average / median (range). Statistically significant differences (p < 0.05) are highlighted in bold font