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Table 4 Influencing factors on HRQoL

From: Costs of illness in amyotrophic lateral sclerosis (ALS): a cross-sectional survey in Germany

A Influencing factors on EQ-VAS score
Variable Change in EQ-VAS score 95% CI p-value
Classified into a care level −14 −22.3 to −5.6 0.001
Impaired in daily activities −24.7 −41.7 to −7.7 0.005
Wheelchair use −8.8 −16 to −4 0.030
Age −0.3 −0.6 to 0 0.034
Permanent attendance of a caregiver necessary −8.3 −16.1 to −0.5 0.037
n 131   
B Influencing factors on EQ-5D-5L™ index value
Variable Change in EQ-index score 95% CI p-value
Permanent attendance of a caregiver necessary −0.25 −0.33 to −0.16 0.000
Wheelchair use −0.17 −0.22 to −0.12 0.000
Classified into a care level −0.13 −0.22 to −0.04 0.005
Impaired in daily activities − 0.15 −0.28 to −0.02 0.023
Invasive ventilation −0.13 −0.28 to 0.03 0.103
Currently working −0.02 −0.12 to 0.08 0.692
n 122   
  1. This multiple linear regression model showed significant influence by mainly of loss of autonomy (classification into a care level, impairment in daily activities, wheelchair use and need of permanent attendance of a caregiver) on HRQoL. The model was adjusted for statistical outliers
  2. Abbreviations: HRQoL health related quality of life, Euro, EQ-VAS score Self-rated health on the visual analogue scale of EuroQol Group EQ-5D-5LTM instrument. health on a visual analogue scale (0–100), CI confidence interval, n number