Costs of illness in amyotrophic lateral sclerosis (ALS): a cross-sectional survey in Germany

Table 4 Influencing factors on HRQoL

A Influencing factors on EQ-VAS score
Variable	Change in EQ-VAS score	95% CI	p-value
Classified into a care level	−14	−22.3 to −5.6	0.001
Impaired in daily activities	−24.7	−41.7 to −7.7	0.005
Wheelchair use	−8.8	−16 to −4	0.030
Age	−0.3	−0.6 to 0	0.034
Permanent attendance of a caregiver necessary	−8.3	−16.1 to −0.5	0.037
n	131
B Influencing factors on EQ-5D-5L™ index value
Variable	Change in EQ-index score	95% CI	p-value
Permanent attendance of a caregiver necessary	−0.25	−0.33 to −0.16	0.000
Wheelchair use	−0.17	−0.22 to −0.12	0.000
Classified into a care level	−0.13	−0.22 to −0.04	0.005
Impaired in daily activities	− 0.15	−0.28 to −0.02	0.023
Invasive ventilation	−0.13	−0.28 to 0.03	0.103
Currently working	−0.02	−0.12 to 0.08	0.692
n	122

This multiple linear regression model showed significant influence by mainly of loss of autonomy (classification into a care level, impairment in daily activities, wheelchair use and need of permanent attendance of a caregiver) on HRQoL. The model was adjusted for statistical outliers
Abbreviations: HRQoL health related quality of life, € Euro, EQ-VAS score Self-rated health on the visual analogue scale of EuroQol Group EQ-5D-5L^TM instrument. health on a visual analogue scale (0–100), CI confidence interval, n number

ISSN: 1750-1172