Fig. 1
From: CLN5 in heterozygosis may protect against the development of tumors in a VHL patient
Genetic pedigree of the family of interest showing information on their VHL and CLN5 genotypes and phenotypes (healthy, lipofuscinosis affected or VHL). Circles represent females and squares represent males. The genotype and phenotype of each family member is indicated underneath. Subject A is the subject of interest carrying a VHL mutation and not developing any tumors. Black arrow indicates first family member diagnosed with VHL