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Table 1 Patient characteristics in 96 cases of BHD

From: Lung function in Birt-Hogg-Dubé syndrome: a retrospective analysis of 96 patients

 Cases with available data, nvalue
Diagnosis by FLCN gene mutation, %9693
Diagnosis by combination of other criteria, %967
Age at diagnosis, mean (SD)9648 (14)
Age at diagnosis in men, mean (SD)5049 (15)
Age at diagnosis in women, mean (SD)4648 (14)
Male sex, %9652
Never-smokers, %9549
Never-smokers in men, %5040
Never-smokers in women, %4560
Active smokers, %9513
Active smokers in men, %5016
Active smokers in women, %459
Former smokers, %9538
Former smokers in men, %5044
Former smokers in women, %4531
Pack-years, mean (SD)4714 (10)
Pulmonary cysts on HRCT, %9395
Cutaneous manifestations, %8979
Renal tumours, %9511
Familial history of pneumothorax and/or pulmonary cysts, %7761
Familial history of BHD, %6060
Dyspnea, %9334
Cough, %9315
Chest pain, %885
Hemoptysis, %911
Pneumothorax (≥ 1), %9659
Age at first pneumothorax, mean (SD)1533 (13)
Number of pneumothoraces, mean (SD)961.6 (2.3)
Pleurodesis, none / unilateral / bilateral, %9456 / 30 / 14