Fig. 7
From: Frizzled related protein deficiency impairs muscle strength, gait and calpain 3 levels
Real-time PCR analysis of Tibialis anterior and Soleus of 10-week-old wild-type (WT) and Frzb−/− mice. a muscle specific genes Pax7, Myod and Myog (> 0.05, p = 0.005 and 0.06 respectively), (b) muscle atrophy-related ubiquitin ligases Fbx32 and Murf1 (all p > 0.05), (c) adipose tissue related genes, Pparg, Adipoq and Fasn (all p > 0.05), (d) genes deregulated in Capn3−/− mice, Park2 and Ky (p = 0.05 and 0.0024), (e) upregulated genes in Frzb−/− mice, Capn3 and Rora (p = 0.014, 0.0025) and (f) genes differentially expressed in muscles from LGMDR1 patients and in the articular cartilage of Frzb−/− mice, Tfrc and Slc16a1 (p = 0.0005, 0.007). Error bars indicate mean ± SEM