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Table 1 Lipodystrophy subtypes (adapted from (2))

From: LipoDDx: a mobile application for identification of rare lipodystrophy syndromes

1 Congenital
 1.1 Generalized
  Type 1 CGL (AGPAT2, recessive, OMIM #608594)
  Type 2 CGL (BSCL2, recessive, OMIM #269700)
  Type 3 CGL (CAV1, recessive, OMIM #612526)
  Type 4 CGL (PTRF, recessive, OMIM #613327)
PPARG -associated CGL (recessive)
  Progressive Encephalopathy with/without lipodystrophy (BSCL2, recessive, OMIM: #615924)
 1.2 Partial
  Type 1 FPLD (Köbberling syndrome; genes unknown, OMIM %608,600)
  Type 2 FPLD (Dunnigan disease; LMNA, (co-)dominant, OMIM #151660)
  Type 3 FPLD (PPARG, dominant, OMIM #604367)
  Type 4 FPLD (PLIN1, dominant, OMIM #613877)
  Type 5 FPLD (CIDEC, recessive, OMIM #615238)
  Type 6 FPLD (LIPE, recessive, OMIM #615980)
  Type 7 FPLD with congenital cataracts, and neurodegeneration (CAV1, dominant, OMIM #606721)
AKT2-linked lipodystrophy (dominant)
MFN2 associated FPLD (recessive)
ADRA2A associated FPLD (dominant)
 1.3 Systemic
  1.3.1 Progeroid syndromes
   Hutchinson-Gilford progeria syndrome (LMNA, dominant, OMIM #176670)
   Néstor-Guillermo progeria syndrome (BANF1, recessive, OMIM #614008)
   Atypical Werner syndrome and atypical progeroid syndrome (de novo, LMNA-associated)
   Werner syndrome (RECQL2, recessive, OMIM #277700)
   Type A mandibuloacral dysplasia (LMNA, recessive, OMIM #248370)
   Type B mandibuloacral dysplasia (ZMPSTE24, recessive, OMIM #608612)
   SHORT syndrome (PIK3R1, dominant, OMIM #269880)
   MDPL syndrome (POLD1, dominant, OMIM #615381)
   Keppen-Lubinsky syndrome (KCNJ6, dominant, OMIM #614098)
   Ruijs-Aalfs syndrome (SPRTN, recessive, OMIM #616200)
   Cockayne syndrome (ERCC6,recessive, OMIM #133540)
   Cockayne syndrome (ERCC6, recessive, OMIM #216400)
   Marfan syndrome with neonatal progeroid –like lipodystrophy (FBN1, dominant, OMIM #616914)
CAV1-associated neonatal onset lipodystrophy syndrome (dominant)
PCYT1A lipodystrophy (recessive)
   Wiedemann Rautenstrauch syndrome (POLR3A, recessive, OMIM #264090)
   Fontaine progeroid syndrome (SLC25A24, de novo, OMIM # 612289)
  1.3.2 Autoinflammatory syndromes
   PRAAS1 (PSMB8, recessive or digenic with PSMA3 or PSMB4, OMIM #256040)
   PRAAS2 (POMP, dominant, OMIM #618048)
   PRAAS3 (PSMB4, recessive or digenic with PSMB9, OMIM # 617591)
   Panniculitis-associated lipodystrophy (OTULIN, recessive, OMIM #617099)
  1.3.3 Others
   Optic atrophy, cataracts, lipodystrophy/lipoatrophy, peripheral neuropathy (OPA3, dominant, OMIM #165300)
2 Acquired
 2.1 Generalized
  Acquired Generalized Lipodystrophy, idiopathic
  Acquired Generalized Lipodystrophy, autoimmune
  Acquired Generalized Lipodystrophy, panniculitis
 2.2 Partial (excluding HIV associated lipodystrophy)
  Acquired partial lipodystrophy (Barraquer-Simons syndrome)
  Lipodystrophy associated with total body irradiation and hematopoietic stem cell transplant
 2.3 Localized
  1. CGL congenital generalized lipodystrophy, FPLD familial partial lipodystrophy, PRAAS Proteasome-associated auto-inflammatory syndrome, MDPL mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome