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Table 11 Grading of levels of Evidence [120]

From: ERNICA guidelines for the management of rectosigmoid Hirschsprung’s disease

Level of Evidence
• I Evidence from at least one randomized controlled trial
• II1 Evidence from well-designed case-control or cohort studies, preferably from more than one research group or centre
• II2 Comparisons between times and places with or without the intervention, or dramatic results of uncontrolled experiments
• III Opinions of respected authorities, based on clinical experience, descriptive studies or reports of expert committees.