Fig. 2
From: Mutations in COL1A1/A2 and CREB3L1 are associated with oligodontia in osteogenesis imperfecta
Clinical and radiographic findings in a 12-year-old boy identified with a CREB3L1 variant. (a) A severe malocclusion with crowding and lateral open bite on the right side and cross-bite on the left. No clinical signs of dentinogenesis imperfecta (DGI). (b) Panoramic radiograph showing absence of six permanent tooth germs in the premolar regions. The radiograph is difficult to interpret due the extensive crowding. No signs of DGI