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Table 2 Significance levels of outcome measures over time

From: Late-onset Pompe disease (LOPD) in Belgium: clinical characteristics and outcome measures

 

nonlinearity

Evolution over time

linear

nonlinear

ActivLim

0.9792

0.0938

0.2405

6MWD

0.0062

0.0102

0.0002

10MWT

0.1195

0.2676

0.0646

MRC sum

0.0431

0.0006

0.0001

FVC sitting

0.5594

0.0077

0.0160

FVC supine

0.7773

0.0151

0.0406

  1. Results (p-values) likelihood-ratio tests from mixed models evaluating the evolution of each of the outcome measures as a function of years since onset. Nonlinearity: is there evidence that the relation is nonlinear (nonlinearity). Linear, nonlinear: is there evidence that the measure changes over time (assuming linearity, and allowing nonlinearity, respectively).