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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Retinal hyperreflective foci in Fabry disease

Fig. 3

Subanalysis of the impact of the clinical course (classical or oligosymptomatic form) and gender of the FD cohort on calculated (a) and subjective (b) vessel tortuosity scores and quantitative (c) and subjective (d) scores of HRF. Male patients with the classic phenotype (n = 9) revealed significantly higher scores in calculated vessel tortuosity (p = 0.0081), subjective vessel tortuosity (p = 0.0018), quantitative score of HRF (p = 0.0015) and subjective score of HRT (p = 0.00098) in comparison with females with the classic phenotype (n = 7). No statistical difference was detected in the evaluated vessel tortuosity and HRF scores between the male (n = 5) and female FD patients (n = 6) with oligosymptomatic phenotype. Statistical analyses of data were performed with the Wilcoxon signed rank test. n.s.: not significant; *p < 0.05; **p < 0.01; ***p < 0.001

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