Fig. 2
From: A systematic review on the burden of illness in individuals with tuberous sclerosis complex (TSC)
Graphical overview of clinical organ manifestations in Tuberous Sclerosis Complex (TSC). Prevalences are given in parentheses after each manifestation. *Prevalence of LAM is given for female patients as there is a high gender-dependency. Prevalences for the majority of manifestations change with age. For sources of the prevalences, please refer to section 3.1 of the manuscript. ADHD = attention deficit hyperactivity disorder, AML = angiomyolipoma, LAM = lymphangioleiomyomatosis, PNET = pancreatic neuroendocrine tumor, SEGA = subependymal giant astrocytoma, SEN = subependymal nodules. Graphic adapted from “Female_shadow_template.svg” and “Girl_diagram_template.svg”, available in the public domain and accessible at https://commons.wikimedia.org/wiki/Human_body_diagrams (original author: Mikael Häggström)