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Table 2 Comparison of OHIP-14 Scores by Age, Gender, Type of Mutation and Mode of Inheritance in LDS

From: Oral health-related quality of life in Loeys-Dietz syndrome, a rare connective tissue disorder: an observational cohort study

Variables% (n)OHIP-14
Mean ± SD
P-value
Age  ns
 Childhood (<  11 yrs)30.3% (10)4.80 ± 6.3 
 Adolescence (>  11 to < 18 yrs)36.4% (12)5.17 ± 5.4 
 Adulthood (>  18 yrs)33.3% (11)8.18 ± 7.6 
Gender  ns
 Male48.5% (16)6.38 ± 6.6 
 Female51.5% (17)5.76 ± 6.5 
Type of Mutation  ns
 TGFBR145.4% (15)6.13 ± 7.4 
 TGFBR236.4% (12)6.00 ± 7.4 
 Others18.2% (6)6.00 ± 7.0 
Mode of Inheritance  ns
 Sporadic83.8% (26)6.50 ± 6.4 
 Familial21.2% (7)4.43 ± 6.9 
  1. Statistical analysis: Wilcoxon Rank-Sum test was employed. ns not significant