Incidence of acquired thrombotic thrombocytopenic purpura in Germany: a hospital level study

Table 2 Number and proportion of aTTP cases related to all TMA (M31.1) and HUS (D59.3) hospitalization cases per participating hospital (2014–2017)

Sum of Cases (2014–2017)	M	HER	HL	BN	F	KI	GP	H	Total
M31.1 PD	30	16	7	12	29	8	23	87	212
aTTP cases (n)	12	5	3	5	18	2	6	28*	79
aTTP cases (%)	40.0%	31.3%	42.9%	41.7%	62.1%	25.0%	26.1%	32.2%	37.3%
M31.1 SD	36	21	9	15	13	28	0	34	156
aTTP cases (n)	2	0	2	1	1	0	0	2*	8
aTTP cases (%)	5.6%	0%	22.2%	6.7%	7.7%	0.0%	0.0%	5.9%	5.1%
D59.3 PD	8	0	23	14	15	8	7	65	140
aTTP cases (n)	0	0	0	0	0	0	0	[1]*	0
aTTP cases (%)	0.0%	0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
D59.3 SD	29	1	9	10	29	10	0	4	92
aTTP cases (n)	0	0	0	0	0	0	0	[1]*	0
aTTP cases (%)	0.0%	0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Total cases (n)	103	38	48	51	86	54	30	190	600
aTTP cases (n)	14	5	5	6	19	2	6	30	87
aTTP cases (%)	13.6%	13.2%	10.4%	11.8%	22.1%	3.7%	20.0%	15.8%	14.5%
Total aTTP (n)	14	5	5	6	19	2	6	30	87
Recurrent aTTP (n)	3	1	0	0	5	0	0	17	26
Recurrent aTTP (%)	21.4%	20.0%	0.0%	0.0%	26.3%	0.0%	0.0%	56.7%	29.9%

ICD-10 M31.1 “Thrombotic Microangiopathy”, ICD-10 D59.3 “Hemolytic Uremic Syndrome”, PD Primary Diagnosis, SD Secondary Diagnosis (SD), M Munich = Medical Clinic and Policlinic IV of the Ludwig-Maximilians-University Munich; HER = Herne = Marien Hospital Herne; HL = Lubeck = University Hospital Schleswig-Holstein, Lubeck; BN = Bonn = University Hospital Bonn; F = Frankfurt am Main = University Hospital Frankfurt; KI = Kiel = University Hospital Schleswig-Holstein, Kiel; GP = Göppingen = Alb Fils Kliniken GmbH; H = Hannover = Clinic for Kidney and Hypertension Disorders; *In Hannover, one aTTP patient was coded as D59.3 PD and one as D59.3 SD; this was identified as miscoded by the study physician; In order to adequately consider these patients, one patient each was classified as M31.1 PD and M31.1 SD and thus assigned to the correct ICD-10 coding

ISSN: 1750-1172