Table 4 Complement autoantibody patterns in clusters of 106 IC-MPGN/C3G patients who have full data-set for all of the autoantibodies
Autoantibody, positivity/ patient | Pattern of autoantibody positivity (number of patients affected) | cluster 1 (n = 46) | cluster 2 (n = 4) | cluster 3 (n = 20) | cluster 4 (n = 36) | Row total |
|---|---|---|---|---|---|---|
0 | None | 17 (28%) | 3 (5%) | 13 (21%) | 28 (46%) | 61 (100%) |
1 | C3NeF (14) | 18 (56%) | 0 (0%) | 6 (19%) | 8 (25%) | 32 (100%) |
C4NeF (8) | ||||||
anti-FH (3) | ||||||
anti-C1q (4) | ||||||
anti-FB (3) | ||||||
2 | anti-C1q + anti-FH (1) | 6 (100%) | 0 (0%) | 0 (0%) | 0 (0%) | 6 (100%) |
anti-C1q + anti-C3 (1) | ||||||
anti-C1q + C4NeF (1) | ||||||
C3NeF + C4NeF (3) | ||||||
> 2 | anti-C1q + anti-FH + anti-FB (1) | 5 (72%) | 1 (14%) | 1 (14%) | 0 (0%) | 7 (100%) |
anti-C1q + anti-FH+ anti-C3 (1) | ||||||
C3NeF + anti-FB + anti- C1q (1) | ||||||
C3NeF + C4NEF + anti-Cq (2) | ||||||
C3NeF + C4NeF + anti-C3 + anti-C1q (1) | ||||||
C3NeF + C4NeF + anti-C3-anti-FB (1) |