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Table 2 Complement parameters of IC-MPGN/C3G patients with and without C4NeF

From: C4 nephritic factor in patients with immune-complex-mediated membranoproliferative glomerulonephritis and C3-glomerulopathy

 

C4NeF positive patients

n = 17

C4NeF negative patients

n = 102

p

serum C4 (0.15–0.55 g/L)

0.2 (0.12–0.26)

0.23 (0.17–0.32)

0.232

serum C3 (0.9–1.8 g/L)

0.33 (0.19–0.98)

0.73 (0.39–01)

0.115

Classical pathway activity (48–103 CH50/mL)

30 (11–54)

46 (28–61)

0.065

Alternative pathway activity (70–125%)

40 (0–67)

63 (3–87)

0.055

C3NeF positivity (< 10%)

7(41)

20 (19.6)

0.063

C1q (60–180 mg/L)

108 (83–138)

102 (83–123)

0.528

anti-C1q (< 52 U/mL)

4 (23.5)

10 (9.8)

0.117

C4d (0.7–6.3 ng/mL)

3.23 (2.6–5.3)

5.46 (3.15–9.27)

0.038

  1. Reference ranges are shown in the first coloumn in parentheses. The data are given as median and interquartile range or number and percentages. P-values are given as the results of χ2 or Mann-Whitney tests
  2. There are some missing values in the following data: C1q (n = 13), C4d (n = 23), anti-C1q (n = 8)
  3. Significance level was determined at a value of p < 0.05