Fig. 1

(a) Kaplan-Meier survival curves of data obtained from symptom onset. The date of symptom onset was reported by the patient as the date when amyloidosis-associated symptoms first occurred. Overall survival at 12, 24, 36, 48, and 60 months after onset was 100.0, 100.0, 88.9, 61.1, and 50.0%, respectively. Numbers below the plot represent number of subjects at risk and at each time point. Cumulative events mean all-cause death in subjects. Total mortality was 72.2% during a median follow-up of 62.5 (45.25,80.25) months. The median survival time from onset was 70.0 (95CI: 48.9–91.1) months. (b) Kaplan-Meier survival curves at confirmed diagnosis. The date of diagnosis was the date on which the diagnosis of amyloidosis was confirmed histologically. Overall survival at 12, 24, 36, 48, and 60 months after diagnosis was 77.8, 55.6, 38.9, 27.8, and 11.1%. Numbers below the plot represent number of subjects at risk and at each time point. Cumulative events means all-cause death in subjects. The median survival time from diagnosis was 30.0 (95CI: 20.3–39.7) months