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Table 5 Simultaneous regression analyses –method forward-- predicting cognitive outcomes from: a) Childhood Phe average; b) childhood Phe SD; c) adolescent/adult Phe average; d) adolescent/adult Phe SD. Analysis A uses adolescent measures; Analysis B uses adult measures

From: Adult cognitive outcomes in phenylketonuria: explaining causes of variability beyond average Phe levels

Dependent Variables

Predictors

Best model

Entered

R2

Adj R2

stand β

p

Analysis - A

 Full IQ

Adolescent Phe average

.23

.21

−0.48

.001

 Mean z-score

Adolescent Phe average

.43

.41

0.38

.01

 

Childhood Phe SD

  

0.36

.01

Analysis - B

 Full IQ

Adult Phe average

.22

.20

−0.47

.001

 Mean z-score

Childhood Phe SD

.41

.39

0.41

.005

 

Adult Phe average

  

0.32

.02

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172