Skip to main content

Table 2 Causes of death among patients with Prader-Willi syndrome by age

From: Causes of death in Prader-Willi syndrome: lessons from 11 years’ experience of a national reference center

Causes of death Children < 18 years old (n = 17), n (%) Adults 18 years old (n = 87),
n (%)
Total
(n = 104)
Respiratory cause 55
Respiratory failurea 2 (12%) 40 (46%)
Respiratory infection 4 (23%) 9 (10%)
Cardiovascular cause 15
Cardiac failure 2 (12%) 6 (8%)
Pulmonary embolism 0 4 (5%)
Other cardiovascular causes 2 (12%) 1 (1%)
Gastrointestinal cause 4
Occlusion 0 3 (3%)
Acute gastroenteritis 1 (6%) 0
Severe infection 4
Sepsis 0 2 (2%)
Other infectious cause 1 (6%) 1 (1%)
Sudden death 4 (23%) 14 (16%) 18
Other causes 0 3 (3%) 3
Unknown cause 1 (6%) 4 (5%) 5
  1. aSignificant difference between children and adults, p = 0.009