Table 2 Causes of death among patients with Prader-Willi syndrome by age
Causes of death | Children < 18 years old (n = 17), n (%) | Adults ≥ 18 years old (n = 87), n (%) | Total (n = 104) |
|---|---|---|---|
Respiratory cause | 55 | ||
Respiratory failurea | 2 (12%) | 40 (46%) | |
Respiratory infection | 4 (23%) | 9 (10%) | |
Cardiovascular cause | 15 | ||
Cardiac failure | 2 (12%) | 6 (8%) | |
Pulmonary embolism | 0 | 4 (5%) | |
Other cardiovascular causes | 2 (12%) | 1 (1%) | |
Gastrointestinal cause | 4 | ||
Occlusion | 0 | 3 (3%) | |
Acute gastroenteritis | 1 (6%) | 0 | |
Severe infection | 4 | ||
Sepsis | 0 | 2 (2%) | |
Other infectious cause | 1 (6%) | 1 (1%) | |
Sudden death | 4 (23%) | 14 (16%) | 18 |
Other causes | 0 | 3 (3%) | 3 |
Unknown cause | 1 (6%) | 4 (5%) | 5 |