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Table 7 Baseline characteristics of HAM-net-registered patients who had been observed for one year (n = 346)

From: Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

 

All patients

(n = 346)

Steroid (S) group

(n = 131)

Steroid-

history (SH) group

(n = 82)

Untreated (U) group (n = 85)

Miscella-

neous (M) group

(n = 48)

p value

Groups with significant difference c)

Sex: Female

260

(75.1%)

97

(74.0%)

60

(73.2%)

67

(78.8%)

36

(75.0%)

0.832 a)

Age at baseline (year)d

61.8 ± 10.8

62.1 ± 9.30

62.2 ± 11.7

61.5 ± 11.9

60.7 ± 11.0

0.875 b)

Age at onset (year)d

44.6 ± 14.8

47.4 ± 13.6

40.4 ± 15.2

45.0 ± 15.0

43.1 ± 16.0

0.009 b)

S > SH

Disease durationd (Time from onset to initial interview)

16.1 ± 11.1

13.9 ± 10.0

20.6 ± 10.8

14.9 ± 11.7

16.7 ± 11.3

< 0.001 b)

SH > S, SH > U

Baseline OMDSd

5.7 ± 2.2

5.7 ± 1.9

6.5 ± 2.5

5.0 ± 2.1

5.8 ± 2.2

< 0.001 b)

SH > S > U

Rapid progressorse

68 (19.7%)

35 (26.7%)

14 (17.1%)

12 (14.1%)

7

(14.6%)

0.075 a)

  1. Statistical methods: a) By chi-square test, b) By analysis of variance, c) By Tukey post hoc tests
  2. dData are expressed as mean ± standard deviation, e Rapid progressors were defined as those who developed OMDS 5 or above within 2 years from the onset of motor symptoms. Abbrevations: OMDS, Osame motor disability score