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Table 3 Patient characteristics and prevalence of comorbidities in HAM-net-registered patients

From: Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

  All the HAM-net-registered patients
(n = 486)
Sex: Female 363 (74.7%)
Age at baseline (year)a 62.0 ± 10.7
Age at onset (year)a 44.8 ± 14.9
Disease durationa (time from onset to the baseline) 16.1 ± 11.3
Baseline OMDSa 5.7 ± 2.3
Rapid progressorsb 96 (19.8%)
Comorbidities Prevalence
Uveitis 37 (7.6%)
Sjogren’s syndrome 18 (3.7%)
Rheumatoid arthritis 13 (2.7%)
Bone Fracture 12 (2.5%)
 Lower limb fracture 5 (1.0%)
 Compression fracture 5 (1.0%)
 Upper limb fracture 0 (0.0%)
Herpes zoster 5 (1.0%)
Interstitial pneumonia 4 (0.8%)
Tuberculosis 0 (0.0%)
Diabetes mellitusc 28 (5.8%)
Cataractc 27 (5.6%)
Glaucomac 12 (2.5%)
  1. aData are expressed as mean ± standard deviation
  2. bRapid progressors were defined as those who developed OMDS 5 or above within 2 years from the onset of motor symptoms
  3. cThese data are based on open-ended questions about comorbidities, Abbreviation: OMDS, Osame motor disability score