Table 6 Studies assessing thyroid hormone status and thyroid cancer in adult GD1 patients
From: Endocrine and metabolic disorders in patients with Gaucher disease type 1: a review
Author (year) | Study population | Main findings |
|---|---|---|
Langeveld et al., 2007 [66] | 22 adult GD1 patients, assessed before and during ERT | Normal thyroid hormone levels in 77% patients at baseline. |
No correlations between serum levels of: 3,3′,5-triiodo-l-thyronine (T3), free thyroxine (fT4), 3,3′,5′-triiodo-l-thyronine (rT3) and baseline REE (kcal/kg per 24 h). | ||
A decrease in fT4 and REE during ERT. No correlation between decrease in fT4 and T(3) and changes in REE. | ||
Lo et al., 2010 [76] | 403 adult GD1 patients, treated and untreated | Two cases of papillary thyroid carcinoma concomitant with haematological malignancies in splenectomised subjects. |