|Strength of evidence of clinical study meta-analysis|
|Number of case reports [+] for the outcome||High to moderate||Low to insufficient|
|≥ 6 [+] of 44 cases (acceptable evidence group)||
(True positives = 3)|
|(False positives = 0)|
|< 6 [+] of 44 cases (unacceptable evidence group)||(False negative = 0)||
(True negatives = 8)|
-6MWT, JROM, Growth, IRR, Pulmonary function, Cardiac, QoL, sleep apnea.