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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Agreement between results of meta-analyses from case reports and clinical studies, regarding efficacy and safety of idursulfase therapy in patients with mucopolysaccharidosis type II (MPS-II). A new tool for evidence-based medicine in rare diseases

Fig. 2

Agreement between the evidence score from the case report meta-analysis and the SOE from the clinical study meta-analysis. Strong confirmatory method. 6MWT: 6-min walk test; CI: Confidence interval; IRR: Infusion-related reaction; JROM: Joint range of motion; QoL: Quality of life; Rho: Spearman correlation coefficient; SOE: Strenght of evidence; uGAGs: Urinary glycosaminoglycans

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