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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Individualized treatment with denosumab in children with osteogenesis imperfecta – follow up of a trial cohort

Fig. 4

a Presents the assessed individual and mean serum calcium levels of ten patients over the observation period. b Presents the urinary calcium/creatinine excretion of seven patients out of spot urine samples after end of the trial. Presented are all data available from the whole observation period. In c, d individual and mean levels of 8 patients of the bone metabolism markers serum parathyroid hormone (PTH), and urinary deoxypyridinoline/creatinine (DPD/Crea) excretion at the different visits (start of trial, end of trial, follow up period) are demonstrated

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