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Table 3 Significantly different clinical and laboratory parameters of well * (Phe < 1200 μmol/l; n = 13) and poorly (Phe > 1200 μmol/l; n = 8) controlled patients

From: The cardiovascular phenotype of adult patients with phenylketonuria

  Well controlled patients Poorly controlled patients  
  mean ± SD mean ± SD p-value
Phe μmol/l 920.2 ± 163.4 1580.0 ± 254.3 < 0.001
Phe mean 5y - μmol/l 829.3 ± 139.2 1247.0 ± 163.4 < 0.001
Total protein intake mean of 5y - g/kg/d 1.0 ± 0.2 0.7 ± 0.0 0.022
Age - years 28.3 ± 8.7 35.3 ± 6.9 0.050
BMI - kg/m2 24.0 ± 2.3 32.1 ± 5.3 0.001
LDLc/HDLc 1.9 ± 0.5 2.3 ± 0.5 0.025
Triglycerides - mmol/l 1.0 ± 0.4 1.9 ± 1.1 0.005
Non-HDLc - mmol/l 2.7 ± 0.4 3.2 ± 0.3 0.017
HDL2c - mmol/l 0.7 ± 0.3 0.5 ± 0.2 n.s.
HDL2c/HDL3c 0.9 ± 0.3 0.6 ± 0.3 n.s.
  1. *according to the German PKU recommendations [23]