Skip to main content

Table 3 Significantly different clinical and laboratory parameters of well * (Phe < 1200 μmol/l; n = 13) and poorly (Phe > 1200 μmol/l; n = 8) controlled patients

From: The cardiovascular phenotype of adult patients with phenylketonuria

 

Well controlled patients

Poorly controlled patients

 
 

mean ± SD

mean ± SD

p-value

Phe ÎĽmol/l

920.2 ± 163.4

1580.0 ± 254.3

< 0.001

Phe mean 5y - ÎĽmol/l

829.3 ± 139.2

1247.0 ± 163.4

< 0.001

Total protein intake mean of 5y - g/kg/d

1.0 ± 0.2

0.7 ± 0.0

0.022

Age - years

28.3 ± 8.7

35.3 ± 6.9

0.050

BMI - kg/m2

24.0 ± 2.3

32.1 ± 5.3

0.001

LDLc/HDLc

1.9 ± 0.5

2.3 ± 0.5

0.025

Triglycerides - mmol/l

1.0 ± 0.4

1.9 ± 1.1

0.005

Non-HDLc - mmol/l

2.7 ± 0.4

3.2 ± 0.3

0.017

HDL2c - mmol/l

0.7 ± 0.3

0.5 ± 0.2

n.s.

HDL2c/HDL3c

0.9 ± 0.3

0.6 ± 0.3

n.s.

  1. *according to the German PKU recommendations [23]