Skip to main content

Table 4 Main neuroradiological findings over follow-up in 9 patients with HHH syndrome

From: Corticospinal tract damage in HHH syndrome: a metabolic cause of hereditary spastic paraplegia

Pt Age at MRI assessment
(yrs)
Brain atrophy Spinal cord
atrophy
Supratentorial Corpus callosum Subtentorial
1 40 + + n.d.
2 27 + n.d.
34 ++ + n.d.
36 ++ + + ++
3 19 ++ ++ +++
4 18 + + + n.d.
23 + + + +
5 25 ++ + n.d.
34 ++ ++ +
6 28 ++ + + n.d
7 12
8 8
9 8 +
  1. Legend: +, mild; ++, moderate; +++, severe; absent, −. n.d not done