Skip to main content

Table 1 Annualized cost per patient

From: Haemophilia A: health and economic burden of a rare disease in Portugal

 

Mild w/o inhibitors

Moderate w/o inhibitors

Severe w/o inhibitors

Inhibitors

Overall

Children

 Direct costs

€ 168

€ 295

€ 90,446

€ 349,973

€ 70,908

  Monitoring

€ 168

€ 295

€ 724

€ 4,968

€ 835

  Prophylaxis

€ 0

€ 0

€ 82,920

€ 40,478

€ 41,377

  ITI

€ 0

€ 0

€ 0

€ 257,972

€ 21,670

  Minor bleedings

€ 0

€ 0

€ 4,649

€ 38,469

€ 5,361

  Major bleedings

€ 0

€ 0

€ 243

€ 8,086

€ 791

 Orthopaedic surgeries

€ 0

€ 0

€ 1,910

€ 0

€ 875

  HIV co-infection

€ 0

€ 0

€ 0

€ 0

€ 0

 Indirect costsa

€ 0

€ 376

€ 2,347

€ 3,286

€ 1,379

  Unemployment

€ 0

€ 0

€ 0

€ 0

€ 0

  Early retirement

€ 0

€ 0

€ 0

€ 0

€ 0

 Work absence

€ 0

€ 376

€ 2,347

€ 3,286

€ 1,379

 Total cost

€ 168

€ 670

€ 92,793

€ 35, 260

€ 72,287

Adults

 Direct costs

€ 168

€ 5,661

€ 76,592

€ 279,429

€ 48,294

  Monitoring

€ 168

€ 239

€ 644

€ 661

€ 402

  Prophylaxis

€ 0

€ 5,422

€ 43,380

€ 48,576

€ 21,319

  ITI

€ 0

€ 0

€ 0

€ 0

€ 0

  Minor bleedings

€ 0

€ 0

€ 25,842

€ 224,212

€ 23,496

  Major bleedings

€ 0

€ 0

€ 3,759

€ 4,923

€ 1,812

 Orthopaedic surgeries

€ 0

€ 0

€ 1,910

€ 0

€ 775

  HIV co-infection

€ 0

€ 0

€ 1,056

€ 1,056

€ 490

  HCV co-infection

€ 0

€ 0

€ 0

€ 0

€ 0

 Indirect costs

€ 310

€ 1,218

€ 6,884

€ 5,736

€ 3,443

  Unemployment

€ 0

€ 51

€ 5,164

€ 5,164

€ 2,405

  Early retirement

€ 0

€ 20

€ 30

€ 118

€ 22

 Work absence

€ 310

€ 1,148

€ 1,690

€ 454

€ 1,016

 Total cost

€ 478

€ 6,880

€ 83,476

€ 285,165

€ 51,737

Overall

 Direct costs

€ 168

€ 4,320

€ 80,055

€ 297,065

€ 53,948

  Monitoring

€ 168

€ 253

€ 664

€ 1,738

€ 510

  Prophylaxis

€ 0

€ 4,067

€ 53,265

€ 46,551

€ 26,333

  ITI

€ 0

€ 0

€ 0

€ 64,493

€ 5,417

  Minor bleedings

€ 0

€ 0

€ 20,544

€ 177,777

€ 18,962

  Major bleedings

€ 0

€ 0

€ 2,880

€ 5,714

€ 1,557

 Orthopaedic surgeries

€ 0

€ 0

€ 1,910

€ 0

€ 800

  HIV co-infection

€ 0

€ 0

€ 792

€ 792

€ 368

 Indirect costs

€ 233

€ 1,008

€ 5,750

€ 5,124

€ 2,927

  Unemployment

€ 0

€ 38

€ 3,873

€ 3,873

€ 1,803

  Early retirement

€ 0

€ 15

€ 23

€ 89

€ 17

 Work absence

€ 233

€ 955

€ 1,854

€ 1,162

€ 1,107

 Total cost

€ 401

€ ,5327

€ 85,805

€ 302,189

€ 56,875

  1. aInformal caregivers