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Table 2 Treatment strategies

From: Natural history of patients with venous thromboembolism and hereditary hemorrhagic telangiectasia. Findings from the RIETE registry

 

Pulmonary

embolism

Deep vein

thrombosis

Odds ratio

(95% CI) /

P value

Patients, N

14

9

 

Duration of therapy,

  Mean days (SD)

260 ± 254

243 ± 195

P = 0.867

  Median days (IQR)

171 (111–335)

177 (86–475)

P = 0.999

Initial therapy,

  Unfractionated heparin

2 (14%)

0

  Low-molecular-weight heparin

10 (71%)

9 (100%)

  Mean LMWH dose (IU/kg/day)

132 ± 50

151 ± 59

P = 0.474

  LMWH doses < 100 IU/kg/day

4 (29%)

2 (22%)

2.33 (0.31–17.55)

  Rivaroxaban

1 (7%)

0

  Inferior vena cava filter (without anticoagulant therapy)

1 (7%)

0

Long-term therapy,

13

9

 

  Low-molecular-weight heparin

7 (54%)

6 (67%)

0.58 (0. 10-3.40)

   Mean LMWH dose (IU/kg/day)

135 ± 35

119 ± 43

P = 0.491

   LMWH < 100 IU/kg/day

1 (8%)

2 (22%)

0.27 (0.02–3.52)

  Vitamin K antagonists

5 (38%)

3 (33%)

1.25 (0. 21-7.41)

  Rivaroxaban

1 (8%)

0

  No anticoagulant drugs

0

0

  1. Abbreviations: SD standard deviation, IQR interquartile range, LMWH low-molecular-weight heparin, IU international units, 95%CI, 95% confidence intervals